Yfull analysis. YFull gives analysis of DNA that is independent of FTDNA.

Yfull analysis Apr 16, 2016 · Looking it up at YFull provides a formed and TMRCA date, phylogenetic equivalents, upstream and downstream SNPs, YFull and 1000 Genomes participants including their country and state when available. To view YFull's interpretation of your mtDNA, select "mtDNA" > "Hg and SNPs" or "MReport" in the menu on the left side of your account home page. They are much more helpful in organizing your results in beneficial format and keeping our YTree updated. Oct 18, 2015 · If two or more of your cluster have taken the Big Y test, and order a YFull analysis of their BAM files (only $49, payable via PayPal when analysis is complete), YFull will define at least one new subclade for you. analysis with vcf file. YFull | Whole genome analysis sheds light on the genetic origin of Huns, Avars and conquering Hungarians YTree v13. If they give you your sub-haplogroup 6 weeks in doesn't that mean your results will be Two samples uploaded to YFull allowed a more detailed analysis of this clade so far only marginally known. Particularly vital for our research into theoretical ancient migrations are the estimated dates for the most recent common ancestors of each lineage that only the YFull analysis provides. Aug 29, 2016 · Yfull is a Moscow-based operation that grinds exceeding slow but careful. Jul 20, 2022 · While this article focuses on an analysis of E-Y20805, I want to ground the analysis of this younger, 2800 year old lineage with what can be determined about the geography of its E-V13 ancestor. 23636 (29 October 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Apr 25, 2020 · I thought that Yseq WGS test combined with YFull analysis might provide better data than just a Big Y test. 23636 (29 October 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Apr 22, 2016 · YFULL gives us a more detailed analysis of BAM files and places us on their Y-Haplotree in relation to other people nearby (i. NextGen Sequence Interpretation, Analysis and comparing your NextGen Y-Chr sequencing data Nov 2, 2019 · YFull offers an analysis that compares your sample to those from eleven testing companies, including FTDNA, who have purchased the service for $49. org YFull offers a lot of technical information as part of their analysis of your male or female uniparental line. See the section on YFull analysis below for a more detailed discussion about the relationship between these three descendants of Samuel Mangum. YTree v13. YFull The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific (1292) 1 2 3 4 5 6 7 8 9 10 11 12 13 Next → YSEQ → YFull Technical progress never has a standstill, and technologies in the field of DNA sequence analysis of next generation have began to develop so promptly recently, that volumes of received initial information exceeds tens gigabytes, and complexity of its processing demands professional interpretation tools. Sep 9, 2022 · YFull is an upload site for Y chromosome and mitochondrial DNA sequencing data that provides deep ancestry analysis. This is especially important to do because E-Y20805 has only 7 geolocated samples on the YFull tree. i reccomend you to have yfull analysis as far as there are more L1b samples on the tree. The main aim of the project is to provide services for the analysis of full Y-chromosome raw data (BAM) files and convenient visualization. And YFull cross checks their work with the ISOGG tree. It is biased against customers of Y-clusters or regions of which descendants do more BigY/NGS testing (Ashkenazi/Europe, Northwest Europe, Georgia, Armenia, Rhine/Germans, Arabia, Russia, others Europe YFull | Mitochondrial DNA sequence analysis of patients with 'atypical psychosis' YTree v13. Apr 18, 2022 · Phylogeny of D-FT75 from FTDNA haplotree restricted to Old World geolocated samples. Server used for this website is located in RU; Russia; 55. YFull and Nebula Genomics At Nebula Genomics we have partnered with YFull to give our users access to the deep ancestry analysis provided by YFull. For Haplogroups like R1a, which is what the Frazers are, they are good at analyzing the information and coming up with new SNPs. 23andme cant Jan 12, 2018 · Apparently that will have to await YFull analysis or analysis by the M223 administrators. If you want to find your exact R1a-Z93 subclade and see if you match medieval Magyars, Huns or other people you need a deeper Y-DNA by FTDNA (Big Y) or Nebula/Dante+Yfull analysis. This second analysis of the ‘ SNP ’ data essentially confirmed what we already had found previously, so the following discussion concerns mainly the new STR markers. 11/3/2019 - YFull Cost Benefit Analysis 10/26/2019 - Release Notes for Update to YFull v7. The e-mail will include a YFull identification number for the shared file. Stuarts dates for a common ancestor to his Grant match and to his Frazer matches increased. Hopefully they will do the YFull analysis so researchers will get a clearer picture and TMRCA estimates that are updated every month. We'll analyze your NextGen Y-Chr RAW data NextGen Sequence Interpretation, Analysis and comparing your NextGen Y-Chr sequencing data YTree v13. On the next page enter your email and name. g. ) clarifY DNA A Big Y analysis service providing personalised reports and diagrams showing placement on the phylogenetic tree. These are preliminary guesses based on early results so are subject to frequent change. YFull aDNA All papers YTree Inheritance of mitochondrial DNA recombinants in double-heteroplasmic families: potential implications for phylogenetic analysis (2) Aug 13, 2025 · The GenArchivist Forum › Human Personal & Genealogical Genetics › Commercial Testing › Other One of the oldest paragroups of J2b gets a little refined by cross-analysis of the known samples and the new YFull sample SRR2098211 Qatar which should form an ancestral haplogroup with the Jewish subcluster Z42983. From their accounts, Nebula Genomics users can easily transfer their Y chromosomal (males) and mitochondrial DNA (males and females) data to YFull and get access to the following results: US Location Latitude: 37. We'll analyze your NextGen Y-Chr RAW data YFull analysis advances the research by adding your male and female lines to the YFull tree, along with a country and regional code that shows other relatives/researchers where you trace your male and female line ancestors. 23696 (07 November 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Jun 22, 2022 · Benefits of YFull Analysis This is a tool for analyzing a mtDNA FASTA but is not intended as a replacement for having your mtDNA FASTA analyzed on YFull. It aims to study the origin in the direct paternal line (Y DNA or Y chromosome) and the direct maternal line (Mitochondrial DNA or mtDNA). In the case of this lineage it's important to also check the FTDNA haplotree because many of the samples were probably not advised to do the YFull analysis. Apr 23, 2016 · YFULL YFULL gives us a more detailed analysis of BAM files and places us on their Y-Haplotree in relation to other people nearby (i. YFull is an ancestry platform that analyzes both your mitochondrial DNA and Y chromosome DNA (if applicable) to track your maternal and paternal heritage. Why would this be the case if it fulfill Mar 22, 2016 · The YFull analysis allowed to confidently place the defining SNPs and give an age estimate for this split according to YFull YTree. I wrote this article to explain how instrumental YFull is in the process of finding one's relatives at a time when many FTDNA-aligned bloggers are discounting the benefits of doing the YFull analysis. 60680000. Anyone interested in contributing matching funds, please let me know how much you will match, for minimum donations of what size, and for how many donations you will contribute. YFull Mitochondrial DNA analysis efficiently contributes to the identification of metastatic contralateral breast cancers (60) J2-M172 Stats from FTDNA Y-DNA Haplotree (BigY) and YFull YTree Current subclades (FamilyTreeDNA) and id’s (YFull YTree v11. 23696 (07 November 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Analysis of Population Substructure in Two Sympatric Populations of Gran Chaco, Argentina (124) 1 2 Next → YTree v13. BAM file). Mar 1, 2025 · Talk about a distant relative. . 23098 (04 July 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Oct 14, 2019 · So, what are the advantages of submitting to YFull? What is YFull? YFull is not a DNA testing company. This should generate a textual hyperlink to your Apr 23, 2016 · YFULL YFULL gives us a more detailed analysis of BAM files and places us on their Y-Haplotree in relation to other people nearby (i. May 28, 2023 · The YFull analysis is not over yet, but judging from other results and the total novels of this sample, the TMRCA of the new subclade should be just slightly younger than that of E-BY4222 (2100ybp on YFull, 2600ybp on FTDNA). YFull has done a great job with the more basal R1b haplogroups, especially with R1b-Z2103. YFull gives analysis of DNA that is independent of FTDNA. The YFull analysis also provides a number of additional features outlined in the table below. This year two new BigY results allowed to further refine the tree further: 327719 Nilsson Haugen Norway with haplotype clearly matching the Montgomery cluster and 170705 Hunt England. 23636 (29 October 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Analysis of Population Substructure in Two Sympatric Populations of Gran Chaco, Argentina (124) 1 2 ← Previous For missing SNPs or to get more of your relatives' geographic distribution on the heatmap, recommend men who have tested WGS or Big Y to do the YFull analysis. NextGen Sequence Interpretation, Analysis and comparing your NextGen Y-Chr sequencing data YFull | Price list YTree v13. 751 Location Longitude: -97. If YFull has low confidence in the accuracy of a reported value, the value appears with a grey background color. Also, what to expect from an mtDNA test? Should I start with the matches if I have any or upload the kit to other genealogical site for further analysis, like Yfull (but as far as I know it's only for analysing y-dna haplogroups, correct me if I'm wrong. who have undergone NGS [Next Generation Sequencing] testing, like the Big Y). Apr 10, 2020 · This is $161 less than the old price of $740. Learn more in our YFull review! Nov 5, 2024 · YFull. Mar 16, 2022 · The extension is a toolkit that enhances the YFull. It does not test, and is therefore unconcerned with physical logistics, it is solely interested in generating further "downstream" SNPs to approach historical times. Jul 5, 2017 · YFull analyzes the Family Tree DNA (FTDNA) BigY test. YFull | Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary Feb 23, 2017 · YFull provides: analysis and comparison of your NextGen Y-Chr sequencing data; a YReport (known SNPs, STRs, novel SNPs, STR and SNP matches); all newly-discovered SNPs added to the Y-series; anonymous use of your data in YFull research projects (if you wish); actual terminal SNPs and positioning on the YTree; individual or group membership Analysis of Population Substructure in Two Sympatric Populations of Gran Chaco, Argentina (124) 1 2 ← Previous Jul 5, 2017 · YFull analyzes the Family Tree DNA (FTDNA) BigY test. Thanks to recent collaboration, YSEQ customers can automatically release their results to YFull for analysis at the discounted rate of $45. org YFull | Analysis and comparing your NextGen Y-Chr sequencing data Meta Keywords of yfull. YFull is an analysis and comparison service for Y-DNA Next Generation Sequencing and full mitochondrial DNA sequences. Only YF02101 as member of the J2a YFull group allows analysis of variant/SNP status (underived/negative, derived/positive, ambiguous, low-confidence, no-read). Can't say the same for FTDNA and their haplotree. Thanks to someone else who uploaded to YFull, I am in a new Haplogroup there called H5’36e. These interpretation and comparison services are more comprehensive than those found at any DNA testing company. However, I have been told that the Big Y tools that you use to interpret your test results and others in your (potential) extended family are very useful. I noticed this the previous time I've done it and I'm wondering if this is how it works. com functionality by providing filtering of samples, additional information about samples on the YFull tree, as well as statistical and visualization tools that facilitate analysis of male and female lines, their geographic distributions and regional diversities. Jan 28, 2023 · If he is FGC36845 then he is M349. No prepayments. Aug 11, 2021 · On the YFull tree we can see this lineage has another child that has been established in Scotland, likely Aryshire, by 750 years ago. 06. YFull will promptly confirm by e-mail the receipt of each order and that it has been able to download the shared raw data. YFull Analysis of mitochondrial DNA diversity in the aleuts of the commander islands and its implications for the genetic history of beringia (38) YTree v13. Feb 1, 2024 · However, with the Deep and Ultra Deep packages, Nebula provides free access to “Deep Ancestry” reports through YFull. I describe several of the most important pieces YFull is a DNA analysis service that allows customers to analyze raw data files (BAM and CRAM) obtained from next-generation sequencing (NGS). The data is collected and analysed and newly discovered single-nucleotide polymorphisms (SNPs) are placed on an experimental Y-tree. Sep 11, 2025 · Yfull: Find all you need to know about how to cancel and unsubscribe from Yfull. Here are my father in law’s Big Y Matches: At first, I thought this was a mistake, so I wrote to the M223 Activity Feed. Comprehensive analysis of common and rare mitochondrial DNA variants in elite Japanese athletes: a case–control study (185) 1 2 ← Previous YTree v13. 23636 (29 October 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) YTree v13. , I am very appreciative of citizen scientists' efforts in R-P312 and R-U106, but the human race i YTree v13. See full list on isogg. The YFull identification number will be added to the YTree in what is called a "predetermined subclade" (a provisional or temporary position) and will be designated as "new" for a period of 45 days I found the analysis by all three companies to teach me something. YFull analysis of kit 447170/ YF05542, Sweden BigY BAM file, and Francalacci et al Sardinian samples ERS256808, combined with results from scientific studies (EB-35147 Alban2 and ERR1025614), allowed to discover a new Z1297 subclade: J2b2-Y23094,B440 – parallel (brother) to Z1295: When I search certain SNPs on my YFull account I see some SNPs that are in the combBED regions, have a large number of reads, and have consistent results with the reads. The homepage contains 10 off-bound links. 23696 (07 November 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) YTree v13. It is rare today in Hungary but was common in medieval Magyars with the Arpad dynasty being R1a-Z94>Z2123. I'm a woman btw so I only purchased the mtdna kit). Well – I just received my YFull analysis today and I went from G-Z30503 to G-Z30503* Meaning… I am a MUTANT…. We'll solve your Y-Chromosome Puzzle! Technical progress never has a standstill, and technologies in the field of DNA sequence analysis of next generation have began to develop so promptly recently, that volumes of received initial information exceeds tens gigabytes, and complexity of its processing demands professional interpretation tools. See subscription plans, pricing, reviews, and feature comparisons. 23696 (07 November 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Two samples uploaded to YFull allowed a more detailed analysis of this clade so far only marginally known. It is not known if the PGP29 sample is also of known Jewish ancestry but a BigY match to B12464 is and shares at least […] Jul 5, 2020 · We value the geographic specificity of the samples in the YFull tree, the ancient samples, samples from scientific studies and the samples from all vendors. Nov 6, 2019 · Stuart’s original YFull analysis was based on his VCF file and his Big Y-700 YFull analysis is based on his BAM file. My understanding is that the BAM analysis is more detailed. For $49 they get estimates of when their most recent common ancestor with men on the YFull tree lived. There answer was that there is a new matching definition: Wait for the Analysis: YTree position usually in days including access to raw data, SNPs and YTree Update including Age estimation can take some weeks, STR Results can take months Jan 14, 2018 · You do not have to pay now; you will receive an invoice when your analysis is complete. ) There work led to expansion of the Y tree and known haplogroups in some areas before the original test company FTDNA was able to do so. com has changed by +98 609 over the past 3 months. 23636 (29 October 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) YFull | MtDNA analysis reveals enriched pathogenic mutations in Tibetan highlanders1 2 3 Next → YFull Whole-mtDNA genome sequence analysis of ancient African lineages (62) Next Generation Sequencing-Based Mitochondrial Genome Analysis In Relation To The Drug- Induced Toxicity In Korean Subjects (118) 1 2 Next → The age of Z467 by YFull YT 3. Haplogroup and thematic projects Jan 29, 2020 · Yfull is not a provider of Y-DNA or NGS tests, but an analysis service for NGS with a database in which data from NGS tests are compared and analyzed, regardless of the provider. Therefore only the haplogroup defined by S25258,FGC21348 can be certified for ISOGG. Do you need to pay before they process it, or will they process it first and you can pay to unlock its results later? For FamilyTreeDNA BIG Y results. Analysis of functional variants in mitochondrial DNA of Finnish athletes (141) 1 2 Next → YTree v13. This is apparently due to the increase of Stuart’s newly found Private SNPs. 23098 (04 July 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) The build/version and reference sequence numbers used by YFull are included in information located with YFull's Check SNPs and Browse RAW data tools and in YFull's Novel SNPs report. 23098 (04 July 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) (The post analysis to extract STR values does take 4-6 months to complete, for unknown reasons. Lineages of the ‘Mangum’ Participants in Big Y Jan 28, 2023 · If he is FGC36845 then he is M349. 73860000; 37. Parallel to Z638,CTS12554 (father of to the known Z1296/CTS8995) this branch seems to be more southern and was not detected so far in Northwest Europe. Do you guys really want to talk about the FTDNA haplotree here? Apr 3, 2020 · The YFull analysis will cost $49 per sample but soon I'll have enough samples such that we will get a discounted rate of $45. Domain registration updated on: 16/7/25. The participants have had NGS testing such as BigY, FGC, or testing from academic studies which is what 1000 Genomes is. What about Links between Greece and Sicily? Starting in the Iron Age, the Greeks played a significant role in colonizing parts of Sicily and southern Italy, which was known as Magna Graecia at the time. But at that time, your "Download Raw Data" dialog window should have a button labeled "Share BAM". Sorry for the long inquiry. 822 Page Title of yfull. Seven of the eight ‘Mangums’ who did Big Y submitted their Big Y BAM files to YFull for additional analysis of the SNP data and extraction of the new STRs. Mar 24, 2019 · At the suggestion of a G-Uncategorized&Root FTDNA group co-admin I uploaded my raw BIG Y 700 data file to YFull for further analysis. However, it says Not used for analysis. * ALT - the abbreviation for alternate alleles, used by YFull to identify the SNP information it finds during its analysis of a sample (e. 02. Donate to J-L283 Haplogroup Research Fund May 17, 2015 · Tweet #5 18 May 2015, 12:12 PM "Share BAM" button is very convenient for YFull analysis After you submit your request to FTDNA for your BAM file, you may have to wait a week until it is available. Still R1a-Z94 is very broad (5000 years old) and it is common from South India to Tatarstan. 09 10/6/2019 - STR Match Finder Correctly Predicted First European J-Z2432, an Azorean 9/27/2019 - New Collaboration System 8/27/2019 - Inspiring Thoughts from PhyloGeography 8/26/2019 - Testing the Accuracy through Simulation 8/23/2019 - Two Improvements Nov 4, 2024 · Next generation sequencing tools YFull A raw data (BAM) interpretation and analysis service (online) for full Y-chromosome data Full Genomes Corporation Offers also a BAM file analysis service (Big Y etc. Knowing how many private SNPs each of these samples has would help us understand how old their are. Date of registry for this domain: 12/8/30. I find big value of YFull is the ability to query your data and compare against others in a group. E-V13 in Five Minutes from YFull YTree How long does Yfull analysis take? For STR data for example. I uploaded my 10th kit from my YSEQ sequencing campaign today and they gave me the analysis for free! Not heard of this before or whether its official or not. 04. You can make yfull. The YFull analysis is being returned very quickly. May 25, 2025 · The GenArchivist Forum › Human Personal & Genealogical Genetics › Commercial Testing › Other May 25, 2025 · The GenArchivist Forum › Human Personal & Genealogical Genetics › Commercial Testing › Other Oct 14, 2019 · So, what are the advantages of submitting to YFull? What is YFull? YFull is not a DNA testing company. What is YFull? YFull is a DNA analysis service that allows customers to analyze raw data files (BAM and CRAM) obtained from next-generation sequencing (NGS). Then click VCF, FTDNA Big Y, and Link to a sharing file. It also identifies our terminal SNP (or SNP block), the SNPs at branching points further upstream (and hence the Shared SNPs we have with our neighbours), and the unique / personal YTree v13. It's also possible that a group of distantly related men, descendants of their common ancestor who lived 370 AD, comigrated together to Poland from somewhere else and didn't leave anyone behind who tested. 34 sounds like a lot to miss if they were indeed high quality. More from YFull At some point, I uploaded my mtDNA results to YFull. 23696 (07 November 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) We'll solve your Y-Chromosome Puzzle! Technical progress never has a standstill, and technologies in the field of DNA sequence analysis of next generation have began to develop so promptly recently, that volumes of received initial information exceeds tens gigabytes, and complexity of its processing demands professional interpretation tools. The most substantial refinement of the M67 tree was possible in the Z467 subclade using 8 BigY results, one of them (B1300/YF02101 Ireland) with additional YFull analysis, gre-77 Greek Hallast et al 2014, Sardinian #845 Francalacci et al 2015, 4 Genome of the […] YTree v13. It would be nice to be able compare across the entire set of public samples though. 00 at 20 June 2025 MTree 1. Paste your online file link. That's it! Now get ready to see what new information you will find. 23696 (07 November 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Nov 20, 2019 · The YFull analysis confirmed that we are more closely related to each other than we are to the Tuscan. Aug 13, 2025 · Remember me The GenArchivist Forum › Human Personal & Genealogical Genetics › Commercial Testing › Other 1 2 Next » YFull Check for new replies Pages (3): « Previous 1 2 3 As posted in the previous posts substream of the J2a-M67 haplogroup other new findings were possible lately. Interesting would be: May 25, 2025 · The GenArchivist Forum › Human Personal & Genealogical Genetics › Commercial Testing › Other Z63 Preliminary Y-DNA Haplogroup Tree - based on FTDNA Big Y results and Yfull analysis NB: This diagram should not be taken as showing definitive branchings and relevant SNPs. Q: Does YFull analyze mtDNA information? A: Since March 2019 YFull analyzes FASTA files with full mtDNA sequence. Dec 7, 2021 · YFull Helper is a Firefox add-on that provides ancestral information and haplogroup analysis in the YTree, along with haplogroup reports by frequency and diversity per country. Analysis in a nutshell: We also want to add that the Alexa Global position for yfull. I am not sure how to read this screen. 23098 (04 July 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Analysis of Population Substructure in Two Sympatric Populations of Gran Chaco, Argentina (124) 1 2 ← Previous Oct 18, 2015 · If two or more of your cluster have taken the Big Y test, and order a YFull analysis of their BAM files (only $49, payable via PayPal when analysis is complete), YFull will define at least one new subclade for you. 00) analysis. 9 is estimated to be over 12,000 years. The number reported under each STR name in the table is the number of repetitions of the STR determined by the YFull analysis. I assume that means 1850 Apr 18, 2022 · Phylogeny of D-FT75 from FTDNA haplotree restricted to Old World geolocated samples. Nov 13, 2020 · The J-L283 Research Fund will purchase/cofund WGS tests and YFull analysis to advance the research into our common origins. com was founded in 2013 and focuses on the interpretation of Y-chromosome sequences. FTDNA has been a*s backwards for the the R1b (U106- P312-) haplogroups for a long time. May 25, 2025 · The GenArchivist Forum › Human Personal & Genealogical Genetics › Commercial Testing › Other Originally Posted by Mikewww, I am not sure how Yfull got into this but they are far behind for the subclades I work with the most. It gives a TMRCA of 1850. This should generate a textual hyperlink to your Mar 18, 2020 · This estimate was obtained from YFull analysis of an exclusively Polish/Slovak cluster of men. e. 00 at 29 September 2025 MTree 1. Though we have not found any errors in our testing with complete mitochondrial sequences, this software is automated, backed by minimap2, and not guaranteed to always produce the correct result. With this reduction, the YSEQ WGS is now competitive in price with Big Y for customers intending to do the YFull analysis. 23696 (07 November 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Once you have received your Big Y results from Family Tree DNA, we then request you submit your raw data to YFull. org t1, bam, sequence, c3, i1, j1, g2a, r1a, r1b, i2a, j2b, haplogroup, e1b1, j2a, g2c, extracting str markers, interpreation, analize raw data, full y sequence, terminal snp YTree v13. YFull | Price list YTree v13. 23636 (29 October 2025) * ybp - Years Before Present (where "present" is defined as AD 1950) Jul 5, 2017 · YFull analyzes the Family Tree DNA (FTDNA) BigY test. dcedg jcdeij vvvw atjg wtkminhr jkror ymig ivtjbf jafpp ujknbe qqbiuksm kwoiw czld prwhuuc oiaxc